| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C10H24N2O2 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Ethambutol is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. It can be used to establish animal models of hyperuricemia and optic neuropathy. It is supplied as a white to off-white solid (C10H24N2O2, MW 204.31) at 98.0% purity.
Physical & Chemical Properties
| CAS Number | 74-55-5 |
|---|---|
| Molecular Formula | C10H24N2O2 |
| Molecular Weight | 204.31 g/mol |
| Purity | 98.0% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | CC[C@H](NCCN[C@@H](CC)CO)CO |
| Signaling Pathway | Anti-infection |
| Solubility | In Vitro: H2O: ≥ 200 mg/mL (978.90 mM) DMSO: 100 mg/mL (489.45 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) * "≥" means soluble, but saturation unknown. |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Ethambutol. Tuberculosis (Edinb), 2008. 88(2): p. 102-5.
[5]. Pham AQ, et al. Pyrazinamide-induced hyperuricemia. P T. 2014 Oct;39(10):695-715.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | ≥ 200 mg/mL (978.90 mM) | — |
| DMSO | 100 mg/mL (489.45 mM) | requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
Data provided by the manufacturer.
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