| Field | Specification |
|---|---|
| Applications | |
| Molecular weight | |
| Molecular formula | C51H62Cl5N9 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
EthD-III is a nucleic acid probe and a red fluorescent stain that can be used to detect dead cells. It enters cells with damaged membranes and binds to nucleic acids, producing bright red fluorescence in dead cells at an excitation/emission of 530/645 nm[1][2]. It is supplied as a dark purple to black solid (C51H62Cl5N9, MW 978.36) at 95.0% purity.
Physical & Chemical Properties
| Molecular Formula | C51H62Cl5N9 |
|---|---|
| Molecular Weight | 978.36 g/mol |
| Purity | 95.0% |
| Appearance | Solid |
| Color | Dark purple to black |
| SMILES | C[NH+](CCC[NH2+]CCC[N+]1=C(C2=CC(N)=CC=C2C3=C1C=C(C=C3)N)C4=CC=CC=C4)CCC[NH2+]CCC[N+]5=C(C6=CC(N)=CC=C6C7=C5C=C(C=C7)N)C8=CC=CC=C8 |
| Signaling Pathway | Cell Cycle/DNA Damage |
| Storage | -20°C, protect from light, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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Embryo-Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis. Adv Sci (Weinh) 2024 Nov;11(43):e2402299. PMID: 39316370
