| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C13H18Cl2N4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
ETP-45835 dihydrochloride is an inhibitor of Erk2, with an IC50 of 18.7 μM. It also inhibits cell proliferation, with an EC50 of 0.9 μM[1]. The manufacturer groups it under the MAPK/ERK Pathway and Stem Cell/Wnt pathway categories.
It has the molecular formula C13H18Cl2N4 and a molecular weight of 301.21 g/mol.
Physical & Chemical Properties
| CAS Number | 2136571-30-5 |
|---|---|
| Molecular Formula | C13H18Cl2N4 |
| Molecular Weight | 301.21 g/mol |
| SMILES | C1(C2=NNC(C3CCNCC3)=C2)=CC=NC=C1.Cl.Cl |
| Signaling Pathway | MAPK/ERK Pathway; Stem Cell/Wnt |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Irene Seipelt, et al. Pyridopyrazine derivatives and their use. US20070123494A1.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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