| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | FBW1B |
| Clonality | |
| Concentration | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human FBW1B |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
Primary AntibodyThis antibody targets FBXW11 and detects endogenous levels of FBXW11 protein.
Validated Applications
| Application | Dilution Guidance |
|---|---|
| Western Blot (WB) | Refer to datasheet for recommended working dilution |
Antibody Specifications
| Target | FBXW11 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Purification | Affinity Purification |
| Molecular Weight | ~59.6 kDa |
| Concentration | 1 mg/ml |
| Immunogen | Synthesized peptide derived from human FBW1B |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Gene ID | Human: 23291; Mouse: 103583 |
| UniProt | Q9UKB1 (Human: Q9UKB1; Mouse: Q5SRY7) |
Scientific Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and| in addition to an F-box| contains multiple WD40 repeats. This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alternative Names
FBW1B
Safety & Handling
| Target | FBXW11 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Purification | Affinity Purification |
| Molecular Weight | ~59.6 kDa |
| Concentration | 1 mg/ml |
| Immunogen | Synthesized peptide derived from human FBW1B |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Gene ID | Human: 23291; Mouse: 103583 |
| UniProt | Q9UKB1 (Human: Q9UKB1; Mouse: Q5SRY7) |
Optimized working dilutions depend on sample type and detection system. Titration is recommended.
| Application | Dilution Note |
|---|---|
| Western Blot (WB) | Refer to datasheet for recommended working dilution |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and| in addition to an F-box| contains multiple WD40 repeats. This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alternative Names
FBW1B
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
