| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, Plendil |
| Cas No. | |
| Form | Light Yellow Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| Source | Synthetic |
| Storage |
Felodipine is an L-type calcium channel blocker with antihypertensive properties. In neuroscience, it has been shown to attenuate cyclosporine-induced hypertrophy in transplanted hearts and may influence calcium-dependent neuronal signaling. Its ability to modulate calcium influx positions it as a candidate for exploring neuroprotective strategies in calcium-mediated neurodegenerative pathways.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S24/25- Avoid contact with shin and eyes
Risk Phrases:
- R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed
- R62 - Possible risk of impaired fertility
Hazard Phrases:
H302
Felodipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-323)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Zahradnikova Z., Minarovic I., Zahradnik I. (2007) J Pharmacol Exp. Ther. 322(2): 638-645.
3. Manzo B.A., Matalka M.S., Ravnan S.L. (2003) Pharmacotherapy. 23(11): 1508-1512.
4. Schwitter J., et al. (1999) J Heart Lung Transplant. 18(10): 1003-1013.
