Ferrostatin-1

Ferrostatin-1 is a potent inhibitor of ferroptosis, an iron-dependent form of regulated cell death characterized by lipid peroxidation. It has demonstrated neuroprotective effects in models of Parkinson’s disease, ischemia-reperfusion injury, and glutamate-induced excitotoxicity. By preventing oxidative lipid damage, Ferrostatin-1 helps preserve neuronal integrity and function. Its ability to mitigate α-synuclein aggregation and reduce neuroinflammation positions it as a promising candidate for therapeutic development in neurodegenerative disease research.

Classification: Skin irritation (Category 2), H315

Safety Phrases:

• S22 - Do not breathe dust.
• S24/25 - Avoid contact with skin and eyes.
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

Hazard statements:

• H315 Causes skin irritation.
• H319 Causes serious eye irritation.

Precautionary statements:

• P260 Do not breathe dust/fume/gas/mist/vapours/spray P264 Wash skin thoroughly after handling.
• P280 Wear protective gloves.
• P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
• P304 + 340 If INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
• P305 + 351+ + 338 IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do so- continue rinsing.
• P333 + 313 If skin irritation or a rash occurs: Get medical advice/attention

Ferrostatin-1 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-525)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).