| Field | Specification |
|---|---|
| Target | |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C25H23FN8O2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
FGFR3-IN-6 is a potent, selective inhibitor of FGFR3 with an IC50 below 350 nM and can be used in cancer research[1]. It has the molecular formula C25H23FN8O2 and a molecular weight of 486.50 g/mol.
Physical & Chemical Properties
| CAS Number | 2833703-72-1 |
|---|---|
| Molecular Formula | C25H23FN8O2 |
| Molecular Weight | 486.50 g/mol |
| SMILES | OC[C@H](C1=CC=C(C=N1)F)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(C#N)C=N5 |
| Target | FGFR3 |
| Signaling Pathway | Protein Tyrosine Kinase/RTK |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Abraham Adedoyin David, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. World Intellectual Property Organization, WO2022187443 A1 2022-09-09
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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