| Field | Specification |
|---|---|
| Target | |
| Alternative names | Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8)|38 kDa FK506-binding protein (38 kDa FKBP, FKBP-38, hFKBP38)|FK506-binding protein 8 (FKBP-8)|FKBPR38|Rotamase|FKBP8|FKBP38 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | FK506 binding protein 8, 38kDa |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes FKBP8. It is validated for ELISA, Western Blot.
Validated Applications
| Applications | ELISA, Western Blot |
|---|---|
| WB | 1:500-1:2000 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
FK506 binding protein 8, 38kDa
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Immunogen | FK506 binding protein 8, 38kDa |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 53 kDa |
| UniProt # | Q14318 |
| Gene ID | 23770 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8)|38 kDa FK506-binding protein (38 kDa FKBP, FKBP-38, hFKBP38)|FK506-binding protein 8 (FKBP-8)|FKBPR38|Rotamase|FKBP8|FKBP38 |
Reactivity Notes
Validated reactivity: Human, Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
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Explore related antibodies and reagents for FKBP8 research from Fine Test, or contact us for alternative formats.
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