| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride; LY-110,140 |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (35 mg/ml); or water (4 mg/ml) |
| Source | Synthetic |
| Storage |
Fluoxetine HCl is a selective serotonin reuptake inhibitor (SSRI) widely used as an antidepressant. It exhibits high selectivity for the serotonin transporter and has demonstrated neuroprotective and neurogenic effects. Fluoxetine enhances neuronal precursor proliferation and differentiation, reduces neuroinflammation, and improves outcomes in models of brain injury and neurodegeneration. It is also being explored for its potential in autism spectrum disorders and cognitive enhancement.
Classification: Danger
GHS Hazard Statements
H302 (98%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (92.1%): Causes skin irritation [Warning Skin corrosion/irritation]
H318 (96%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H400 (58.4%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
Precautionary Statement Codes:
P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, P391, and P501
Fluoxetine HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-631)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
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2. P Benfield et al. Drugs 1986 32:481
3. A Benvenuto et al. Brain Dev. 2013 35:119
4. FY Liu et al. J. Neuroinflammation 2018 15:347
5. EA Chang et al. Int. J. Dev. Biol. 2010 54:707