Flupirtine maleate

SKU:BHB11900164
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Flupirtine maleate is a research-grade small-molecule activator of Kv7 channel supporting Neuroscience and Ion Channels research. Supplied as a white solid with >98% purity (CAS 75507-68-5, MW 420.4) soluble in DMSO and ethanol; store at -20°C. For research use only.
Cas No. 75507-68-5
Molecular Formula C15H17FN4O2•C4H4O4
Purity >98% (HPLC)
Application Notes Kv7 channel activator
Options selector
Catalog no. Size
SIH-376-10MG 10 mg
SIH-376-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 10 mg, 50 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-376
Activity
  • Activator
Alternative Names N-[2-Amino-6-[[4-fluorophenyl)methy-l]amino]-3-pyridinyl]carbamic acid ethyl ester maleate
Cas No. 75507-68-5
Form White solid
Molecular Weight 420.4
Product Type
  • Biochemicals
  • Small Molecules
Purity >98% (HPLC)
Shipping Shipped Ambient
SMILES CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=C\C(=O)O)\C(=O)O
Solubility Soluble in DMSO (100 mM) and ethanol (10 mM)
Source Synthetic
Storage -20ºC

Flupirtine maleate is a non-opioid analgesic with neuroprotective properties, acting as a selective neuronal potassium channel opener and NMDA receptor antagonist. In neurodegenerative disease research, flupirtine has been shown to reduce excitotoxicity, oxidative stress, and apoptosis in neuronal cells. It enhances mitochondrial function and supports neuronal survival, making it a candidate for therapeutic intervention in conditions such as Alzheimer’s and Parkinson’s disease. Its dual action on pain modulation and neuroprotection underscores its relevance in neuroscience.

Classification: Caution: Substance not yet fully tested.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Flupirtine maleate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-376)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Naser SM., Sarkar N., Biswas A., Kamal F., Prakash R., Rahaman QM., Das AK. (2012) J Indian med Assoc. 110(3): 158-60.
2. Harish S., Bhuvana K., Bengalorkar G. and Kumar TN. (2012) J Anaethesiol Clin Pharmacol. 28(2): 172-177.

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