| Field | Specification |
|---|---|
| Alternative names | N-[2-Amino-6-[[4-fluorophenyl)methy-l]amino]-3-pyridinyl]carbamic acid ethyl ester maleate |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C15H17FN4O2•C4H4O4 |
| Purity | |
| Bioactivity | Activator |
| Activity | |
| Solubility | Soluble in DMSO (100 mM) and ethanol (10 mM) |
| SMILES | |
| InChIKey | |
| Form | White solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Flupirtine maleate is a non-opioid analgesic with neuroprotective properties, acting as a selective neuronal potassium channel opener and NMDA receptor antagonist. In neurodegenerative disease research, flupirtine has been shown to reduce excitotoxicity, oxidative stress, and apoptosis in neuronal cells. It enhances mitochondrial function and supports neuronal survival, making it a candidate for therapeutic intervention in conditions such as Alzheimer’s and Parkinson’s disease. Its dual action on pain modulation and neuroprotection underscores its relevance in neuroscience.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Flupirtine maleate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-376)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. Harish S., Bhuvana K., Bengalorkar G. and Kumar TN. (2012) J Anaethesiol Clin Pharmacol. 28(2): 172-177.
