| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C16H15N3O4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
FOY 251 free base, an anti-proteolytic active metabolite of Camostate, functions as a proteinase inhibitor[1][2]. It also inhibits SARS-CoV-2 infection in a cell-based assay[3]. It has a molecular formula of C16H15N3O4 and a molecular weight of 313.31 g/mol.
Physical & Chemical Properties
| CAS Number | 71079-08-8 |
|---|---|
| Molecular Formula | C16H15N3O4 |
| Molecular Weight | 313.31 g/mol |
| SMILES | O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1 |
| Signaling Pathway | Metabolic Enzyme/Protease; Anti-infection |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
FOY 251 free base inhibits equivalent current in M-1 cells in a dose-dependent manner[2]. FOY-251 free base blocks the proteolytic activity of prostasin[2].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics. Nucleic Acids Res 2021 Jan 8;49(D1):D1113-D1121. PMID: 33166390
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo. Res Sq 2024 Nov 21:rs.3.rs-5454588. PMID: 39606435
