| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2,2'-{(19-Amino-11,16,18-trihydroxy-5,9-dimethyl-6,7-icosanediyl)bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid |
| Cas No. | |
| Form | Beige Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 10 mM in DMSO |
| Source | Synthetic |
| Storage |
Fumonisin B1 is a mycotoxin that inhibits ceramide synthase, disrupting sphingolipid metabolism. It is used in neuroscience to model neurotoxicity and study the effects of altered lipid signaling on neural development and apoptosis. Fumonisin B1 exposure has been linked to neural tube defects and other neurodevelopmental abnormalities, making it a compound of interest in neurotoxicology research.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
- R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
- R60- May impair fertility
- R61- May cause harm to the unborn child
Hazard Phrases:
H351
Precautionary Phrases:
P281
Fumonisin B1 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-234)
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2. Stockmann-Juvalla H., and Savolainen K. (2008) Human and Exp. Toxicology. 27: 799-809.