| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C29H32ClN5O3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
G12Si-2 is an analog of G12Si-1 that serves as a negative control tool; unlike its parent compound, it is not a covalent inhibitor of the G12S mutant of K-Ras[1]. Its molecular formula is C29H32ClN5O3, with a molecular weight of 534.05 g/mol.
Physical & Chemical Properties
| CAS Number | 2946593-43-5 |
|---|---|
| Molecular Formula | C29H32ClN5O3 |
| Molecular Weight | 534.05 g/mol |
| SMILES | ClC1=CC=CC2=CC=CC(N3CC4=C(CC3)C(N5CC6C(CC5)OC6=O)=NC(OC[C@@H]7CCCN7C)=N4)=C21 |
| Signaling Pathway | GPCR/G Protein; MAPK/ERK Pathway |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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