| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C24H32N6O2S |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Glutaminyl Cyclase Inhibitor 3 is a designed anti-Alzheimer's compound and a potent inhibitor of human Glutaminyl Cyclase (GC), with an IC50 of 4.5 nM. It significantly reduced brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions[1]. It has the molecular formula C24H32N6O2S and a molecular weight of 468.61 g/mol.
Physical & Chemical Properties
| CAS Number | 2092921-50-9 |
|---|---|
| Molecular Formula | C24H32N6O2S |
| Molecular Weight | 468.61 g/mol |
| SMILES | COC1=C(OCCCCC2=CC(N)=NC=C2)C=CC(NC(NCCCN3C(C)=CN=C3)=S)=C1 |
| Signaling Pathway | Neuronal Signaling |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Biological Activity
IC50 & Target
IC50: 4.5 nM (hGC)[1].
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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