| Field | Specification |
|---|---|
| Alternative names | GR3027 |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C21H31NO2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Golexanolone, also known as GR3027, is a GABAA receptor modulating steroid antagonist. In hyperammonemic rats, it reduces both peripheral inflammation and neuroinflammation and improves cognitive and motor function[1]. It has a molecular formula of C21H31NO2 and a molecular weight of 329.48 g/mol.
Physical & Chemical Properties
| CAS Number | 2089238-18-4 |
|---|---|
| Molecular Formula | C21H31NO2 |
| Molecular Weight | 329.48 g/mol |
| SMILES | C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@](O)(CC2)C#C)([H])[C@@]4([H])[C@](CC3)(/C(CC4)=N/O)C |
| Signaling Pathway | Membrane Transporter/Ion Channel; Neuronal Signaling |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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