| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C30H26O10 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Gossypolone is an inhibitor of the RNA-binding protein Musashi-1 with a Ki of 12 nM that disrupts the Musashi-numb RNA interaction by directly binding to the RBD1 domain of the MSI1 protein, and can be used in cancer research[1]. It is supplied as a light yellow to brown solid (C30H26O10, MW 546.52) at 96.28% purity.
Physical & Chemical Properties
| CAS Number | 4547-72-2 |
|---|---|
| Molecular Formula | C30H26O10 |
| Molecular Weight | 546.52 g/mol |
| Purity | 96.28% |
| Appearance | Solid |
| Color | Light yellow to brown |
| SMILES | O=CC1=C(C(O)=C(C2=C1C(C(C(C3=O)=C(C(C4=C3C(C=O)=C(C(O)=C4C(C)C)O)=O)C)=C(C2=O)C)=O)C(C)C)O |
| Signaling Pathway | Cell Cycle/DNA Damage |
| Storage | 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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