| Field | Specification |
|---|---|
| Target | |
| Alternative names | Gastrin-releasing peptide (GRP)|Neuromedin-C Alternative names: GRP-10|GRP18-27|GRP |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | gastrin-releasing peptide |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes GRP. It is validated for ELISA, Western Blot, Immunohistochemistry.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry |
|---|---|
| WB | 1:500-1:2000 |
| IHC | 1:20-1:200 |
| IF | 1:20-1:200 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
gastrin-releasing peptide
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Immunogen | gastrin-releasing peptide |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 16 kDa, 32 kDa |
| UniProt # | P07492 |
| Gene ID | 2922 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Gastrin-releasing peptide (GRP)|Neuromedin-C Alternative names: GRP-10|GRP18-27|GRP |
Reactivity Notes
Validated reactivity: Human. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for GRP research from Fine Test, or contact us for alternative formats.
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