| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the HLA-ABC antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
HLA-ABC Antibody / MHC I is an antibody targeting HLA-ABC. Host: Rabbit. Monoclonal. Clone: MHC-I/8147R. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: HLA-ABC.
- Immunogen: A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen fo….
- Species reactivity: Human.
- Localization: Cell Surface.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
Major Histocompatibility Complex (MHC) is a genetic region on chromosomes composed of tightly linked highly polymorphic gene loci that encode cell surface specific proteins, depending on the structure and function of genes and coding products. We divide MHC into class I (telomeric), class II (centromeric) and class III gene regions.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
