HSPC:Cholesterol:DSPG-PEG2000 Liposome

What it means: 10 mg/ml — the total lipid concentration of the suspension.

Why it matters:

• Lipid concentration tells you how much liposome material you add per volume.
• It is the basis for calculating doses and lipid-to-cargo ratios.
• Knowing it helps you dilute liposomes to a target lipid amount.
• It allows comparison between liposome preparations.
• Stating the value makes your methods easy to report and repeat.
• Dilution changes the lipid concentration but not the composition.
• Lipid amount is often used to normalize doses between liposome preparations.
• A known lipid amount helps when you compare uptake or release between preparations.

For this product: The suspension contains 10 mg/ml total lipid, 10 ml per bottle.

Tip: Dilute liposomes in the same histidine–sucrose buffer to keep conditions constant.

What it means: 200 mM ammonium sulfate — the ammonium salt gradient used to load drugs into the liposomes.

Why it matters:

• The uncharged form of an amine drug crosses the bilayer, becomes protonated inside and is trapped.
• Remote loading usually reaches higher encapsulation than passive loading.
• The loading step is a simple incubation of drug and liposomes.
• The drug-to-lipid ratio decides how much drug can be loaded.
• Removing free drug after loading gives a clean liposome preparation.
• Loading capacity depends on the drug, so a test load at several drug-to-lipid ratios is useful.
• Incubation temperature and time affect how completely the drug loads.

For this product: The interior contains 200 mM ammonium sulfate, the ammonium salt gradient used to load compounds with amine groups.

Tip: Remove unloaded compound after loading before downstream tests.

What it means: Cold, Not Frozen — how the product is shipped.

Why it matters:

• The shipping condition tells you what to expect when the package arrives.
• Unpacking promptly lets you check the contents against the order.
• Checking the package on arrival helps you spot transport problems early.
• Storage conditions can differ from shipping conditions, so confirm them before the package arrives.
• Recording the arrival date and condition helps if questions come up later.
• Arranging for someone to receive the package avoids delays when it arrives.
• The shipping condition is chosen to keep the product as described during transport.

For this product: Ships cold, not frozen. Please contact us to confirm storage conditions.

Tip: Do not freeze liposomes; check the package on arrival and contact us right away if anything is damaged or missing.