| Field | Specification |
|---|---|
| Target | |
| Alternative names | IDUA ELISA Kit; Alpha-L-iduronidase ELISA Kit; EC 3.2.1.76 ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, cell lysates, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
α-L-iduronidase (IDUA) is a biological molecule commonly studied in signal transduction research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: P35475
Biological context
Researchers often monitor α-L-iduronidase in serum, plasma, cell lysates, and tissue homogenates to better understand themes such as mechanistic biology studies, biomarker-focused profiling, and disease-model research. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in α-L-iduronidase may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, complementary pathway markers and controls appropriate to the biological model) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, α-L-iduronidase may also appear under names such as IDUA and Alpha-L-iduronidase. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that α-L-iduronidase participates in.
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