| Field | Specification |
|---|---|
| Target | |
| Alternative names | JKT 14 ELISA Kit; JTK14 ELISA Kit; TIE ELISA Kit; Tie1 ELISA Kit; TIE1_HUMAN ELISA Kit; Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 ELISA Kit; Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains ELISA Kit; Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 ELISA Kit; Tyrosine protein kinase receptor Tie 1 ELISA Kit; Tyrosine-protein kinase receptor Tie-1 ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
tyrosine kinase with immunoglobulin-like and EGF-like domains 1,Tie-1 (TIE1) is a biological molecule commonly studied in cardiovascular research. Immunoglobulins are antibody proteins central to humoral immunity and antigen-specific responses.
UniProt: P35590
Biological context
Researchers often monitor tyrosine kinase with immunoglobulin-like and EGF-like domains 1,Tie-1 in serum, plasma, and tissue homogenates to better understand themes such as vascular biology and endothelial function, cardiac remodeling and injury responses, and thrombosis and hemostasis. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in tyrosine kinase with immunoglobulin-like and EGF-like domains 1,Tie-1 may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, endothelial markers, coagulation-related proteins, and cardiac injury markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, tyrosine kinase with immunoglobulin-like and EGF-like domains 1,Tie-1 may also appear under names such as JKT 14 and JTK14. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that tyrosine kinase with immunoglobulin-like and EGF-like domains 1,Tie-1 participates in.
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