| Field | Specification |
|---|---|
| Target | |
| Alternative names | UCMA ELISA Kit; C10orf49 ELISA Kit; Unique cartilage matrix-associated protein [Cleaved into: Unique cartilage matrix-associated protein C-terminal fragment ELISA Kit; Ucma-C ELISA Kit; Gla-rich protein ELISA Kit; GRP)] ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
upper zone of growth plate and cartilage matrix associated (UCMA) is a biological molecule commonly studied in developmental biology research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q8WVF2
Biological context
Researchers often monitor upper zone of growth plate and cartilage matrix associated (UCMA) in serum, plasma, and tissue homogenates to better understand themes such as cell differentiation programs, tissue morphogenesis, and stem cell regulation. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in upper zone of growth plate and cartilage matrix associated (UCMA) may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, morphogen-related factors, differentiation markers, and signaling ligands) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, upper zone of growth plate and cartilage matrix associated (UCMA) may also appear under names such as UCMA and C10orf49. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that upper zone of growth plate and cartilage matrix associated (UCMA) participates in.
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Association of UCMA levels in serum and synovial fluid with severity of knee osteoarthritis
Okuyan HM, et al,International Journal of Rheumatic Diseases,2019