| Field | Specification |
|---|---|
| Target | |
| Alternative names | CTRCT30 ELISA Kit; Epididymis luminal protein 113 ELISA Kit; FLJ36605 ELISA Kit; HEL113 ELISA Kit; VIM ELISA Kit; VIME_HUMAN ELISA Kit; Vimentin ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
vimentin (VIM) is a biological molecule commonly studied in cancer research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: P08670
Biological context
Researchers often monitor vimentin in serum, plasma, and tissue homogenates to better understand themes such as tumor microenvironment biology, cell proliferation and apoptosis, and metastasis and invasion pathways. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in vimentin may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, cell-cycle regulators, invasion/ECM markers, and immune-oncology mediators) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, vimentin may also appear under names such as CTRCT30 and Epididymis luminal protein 113. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that vimentin participates in.
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Differential Associations of PIVKA-II with Epithelial and Mesenchymal Features in HCC and PDAC
F Antonella, C Gaia, V Valentina, M Matteo,International Journal of Molecular Sciences,2025
Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis
Su L, et al,Scientific Reports,2019