| Field | Specification |
|---|---|
| Target | |
| Alternative names | DBP ELISA Kit; DBP/GC ELISA Kit; GC ELISA Kit; Gc globulin ELISA Kit; Gc-globulin ELISA Kit; GRD3 ELISA Kit; Group specific component ELISA Kit; Group specific component vitamin D binding protein ELISA Kit; Group-specific component ELISA Kit; hDBP ELISA Kit; VDB ELISA Kit; VDBG ELISA Kit; VDBP ELISA Kit; Vitamin D binding alpha globulin ELISA Kit; Vitamin D-binding protein ELISA Kit; VTDB_HUMAN ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
Vitamin D-binding protein (GC) is a biological molecule commonly studied in signal transduction research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: P02774
Biological context
Researchers often monitor Vitamin D-binding protein in serum, plasma, and tissue homogenates to better understand themes such as mechanistic biology studies, biomarker-focused profiling, and disease-model research. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in Vitamin D-binding protein may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, complementary pathway markers and controls appropriate to the biological model) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, Vitamin D-binding protein may also appear under names such as DBP and DBP/GC. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that Vitamin D-binding protein participates in.
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Reduction in circulating vitamin D binding protein in patients with multiple sclerosis
Z Maghbooli,BMC Neurology,2021
Associations between Vitamin D and Type 2 Diabetes Mellitus: The Role of Vitamin D Receptor and Binding Protein
ES Arafat,Journal of Diabetes Mellitus,2020
Characterization of differentially expressed plasma proteins in patients with acute myocardial infarction
Y Pan,Journal of Proteomics,2020
Exploration of candidate serum biomarkers potentially related to the chronic pain condition in Medication-overuse headache
Pellesi L, et al,Bmc Neurology,2019
Correlation between cervical consistency index and vitamin D binding protein in prediction of preterm labour
Eman A. Alkholy1.et al,Journal of American Science,2016
Predictive value of serum actin-free Gc-globulin for complications and outcome in acute liver failure
Bagchi A.et al,J Viral Hepat.,2015
An analysis of the association between the vitamin D pathway and serum 25-hydroxyvitamin D levels in a healthy Chinese population
Zhang Z et al,J Bone Miner Res.,2013