Hydroxychloroquine Impurity F

SKU:BHB21900791
Overview
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Hydroxychloroquine Impurity F (CAS 6281-58-9) is a drug metabolite. Relevant to Metabolic Enzyme/Protease research. Molecular formula C14H15ClN2, molecular weight 246.74 g/mol.
CAS Number 6281-58-9
Molecular Weight 246.74 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-131263-5MG 5 mg
HY-131263-10MG 10 mg
HY-131263-25MG 25 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 10 mg, 25 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 6281-58-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 246.74
Molecular formula C14H15ClN2
SMILES CC1N(C2=CC=NC3=CC(Cl)=CC=C23)CCC1
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-131263
Main SKU BHB21900791
Drug Metabolites & Impurities

Compound Overview

Hydroxychloroquine Impurity F is an impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent that can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling and efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3]. It has the molecular formula C14H15ClN2 and a molecular weight of 246.74 g/mol.

Physical & Chemical Properties

CAS Number 6281-58-9
Molecular Formula C14H15ClN2
Molecular Weight 246.74 g/mol
SMILES CC1N(C2=CC=NC3=CC(Cl)=CC=C23)CCC1
Signaling Pathway Metabolic Enzyme/Protease
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6.

[2]. Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40.

[3]. Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Mar 9. pii: ciaa237.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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