Hypericin

SKU:BHB11900072
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Hypericin is a research-grade small-molecule inhibitor of Protein kinase C supporting Cancer and Apoptosis research. Supplied as a dark red solid with >98% purity (CAS 548-04-9, MW 504.45) Soluble to 10 mM in ethanol and to 50 mM in DMSO; store at -20°C. For research use only.
Cas No. 548-04-9
Molecular Formula C30H16O8
Purity >98%
Application Notes Protein kinase C inhibitor
Options selector
Catalog no. Size
SIH-250-1MG 1 mg
SIH-250-10MG 10 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 1 mg, 10 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-250
Activity
  • Inhibitor
Alternative Names 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Cas No. 548-04-9
Form Dark Red Solid
Molecular Weight 504.45
Product Type
  • Biochemicals
  • Small Molecules
Purity >98%
Shipping Shipped Ambient
SMILES CC1=CC(=C2C3=C4C5=C(C(=CC(=C5C2=O)O)O)C6=C7C4=C8C(=C13)C(=CC(=C8C(=O)C7=C(C=C6O)O)O)C)O
Solubility Soluble to 10 mM in ethanol and to 50 mM in DMSO
Source Synthetic
Storage -20ºC

Hypericin is a naturally derived naphthodianthrone compound known for its antibiotic and kinase-inhibitory properties. It inhibits dopamine beta-hydroxylase, leading to elevated dopamine levels, which may influence mood and cognitive function. Hypericin's ability to accumulate in specific tissues, including tumors and potentially inflamed neural tissue, makes it a candidate for diagnostic imaging and targeted therapy. Its photosensitizing properties also enable its use in photodynamic therapy. In neuroscience, hypericin is being explored for its effects on neurotransmitter regulation and neuroinflammation.

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hypericin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-250)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Hopfner M., et al. (2003) Int J Colorectal Dis. 18(3): 239-247.
2. Agostinis, et al. (2002) Int J Biochem Cell Biol. 34: 221.

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