| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C10H10O3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Ibuprofen Impurity K is an impurity of Ibuprofen, which is a COX-1/COX-2 inhibitor with anti-inflammatory activity. It also functions as an intermediate in the synthesis of loxoprofen[1]. It has the molecular formula C10H10O3 and a molecular weight of 178.18 g/mol.
Physical & Chemical Properties
| CAS Number | 43153-07-7 |
|---|---|
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 g/mol |
| SMILES | O=C(O)C(C)C1=CC=C(C=O)C=C1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
[1]. Zhu G L, et al. Preparation method for substituted phenylacetic acid derivatives. CN106316837A, China, 2015.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
Ibuprofen Impurity K (III-1) is the key aldehyde-substituted phenylpropanoic acid precursor for synthesizing intermediate II‑1. Acid/base-catalyzed condensation with cyclopentanone converts it to II‑1, which a one-step reduction then turns into loxoprofen[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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