ICMT-IN-37

SKU:BHB21902271
Overview
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ICMT-IN-37 (CAS 1313602-87-7) is an ICMT inhibitor. Relevant to GPCR/G Protein research. Molecular formula C22H28ClNO, molecular weight 357.92 g/mol.
CAS Number 1313602-87-7
Molecular Weight 357.92 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-157105-50MG 50 mg
HY-157105-100MG 100 mg
HY-157105-250MG 250 mg
Available Options

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  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 1313602-87-7
Applications
  • Functional Assay (In Vitro)
Molecular weight 357.92
Molecular formula C22H28ClNO
SMILES CC1=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=CC=C1Cl
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-157105
Main SKU BHB21902271
Inhibitors

Compound Overview

ICMT-IN-37 is an inhibitor of ICMT, with an IC50 of 0.308 μM[1]. It has the molecular formula C22H28ClNO and a molecular weight of 357.92 g/mol.

Physical & Chemical Properties

CAS Number 1313602-87-7
Molecular Formula C22H28ClNO
Molecular Weight 357.92 g/mol
SMILES CC1=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=CC=C1Cl
Signaling Pathway GPCR/G Protein
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Biological Activity

IC50 & Target

IC50: 0.308 μM (ICMT)[1]

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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