| Field | Specification |
|---|---|
| Alternative names | LL-Z 1272ζ |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C25H31ClO6 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Ilicicolin F, also known as LL-Z 1272ζ, is a fungal metabolite found in Fusarium with diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo, with IC50 values of 0.43 and 0.37 μM, respectively, but does not inhibit the E. coli ubiquinol oxidase cytochrome bd (IC50 = 85 μM). It is active against the fungi A. fumigatus and C. albicans, with MICs of 1.66-3.33 and 6.66-13.33 μg/mL, respectively, and is cytotoxic to HeLa cells with an EC50 of 0.003 μg/mL. It has the molecular formula C25H31ClO6 and a molecular weight of 462.96 g/mol.
Physical & Chemical Properties
| CAS Number | 22738-98-3 |
|---|---|
| Molecular Formula | C25H31ClO6 |
| Molecular Weight | 462.96 g/mol |
| SMILES | O=CC1=C(C)C(Cl)=C(O)C(C/C=C(C)/C=C/[C@@]2(C)[C@H](C)[C@@H](OC(C)=O)CC([C@@H]2C)=O)=C1O |
| Signaling Pathway | Anti-infection |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Ellestad, et al. Some new terpenoid metabolites from an unidentified fusarium species. Tetrahedron 25(6), 1323-1334 (1969).
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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