| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Iniparib, 4-Iodo-3-nitrobenzamide, BSI-201, 4-iodo-3-nitro-benzamide, Iniparib (BSI-201) |
| Cas No. | |
| Form | White to beige powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (5 mg/ml) |
| Source | Synthetic |
| Storage |
BSI 201 is a small molecule inhibitor of poly(ADP-ribose) polymerase 1 (PARP1), an enzyme involved in DNA repair and cellular stress responses. While widely studied in oncology for its ability to induce synthetic lethality in tumor cells with DNA repair deficiencies, PARP1 inhibition is also relevant to neurodegenerative disease research. Excessive PARP1 activation has been linked to neuronal death in conditions such as stroke, Parkinson’s disease, and Alzheimer’s disease. By modulating DNA repair and inflammatory pathways, BSI 201 may help mitigate neuronal damage and promote neuroprotection. Its dual relevance to cancer and neuroscience underscores its value in translational research.
Classification: D2B Toxic Material Causing Other Toxic Effects - Moderate eye irritant
Hazard statement(s):
- H302 Harmful if swallowed.
- H319 Causes serious eye irritation.
Precautionary statement(s):
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Iniparib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-539)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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