| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | Mouse IgG light chain |
| Isotype | |
| Product Type | |
| Reactivity | |
| Shipping | |
| Storage | |
| Target |
Features & Benefits
50kD or 25kD protein detection on Western blots after Immunoprecipitation is often suffered from heavy or light chain blotting contamination). Abbkine's IPKine™ products solve these problems through less background noise, and enhanced accuracy). Their light chain/Fc fragment specific optimization will eliminate heavy/light chain interference, while serum proteins absorbed minimize cross-reactivity with immunoglobulins from other species which may be present on blots).
Background
Abbkine secondary antibodies are available conjugated to enzyme, biotin or fluorophore for use in a variety of antibody-based applications including Western Blot, ImmunoHistoChemistry, ImmunoFluorescence, Flow Cytometry and ELISA. We offer high quality secondary antibodies from goat, rabbit and donkey sources for your each application.
Others
The antibody reacts with kappa light chains on mouse IgG, while it doesn’t react with the heavy chain of mouse IgG. It's cross-reaction with human, rabbit, rat, goat, sheep and bovine serum proteins has been specialized minimized, while it may cross-react with immunoglobulins from other species. It has no reactivity on non-immunoglobulin serum proteins
MAMDC2, a gene highly expressed in microglia in experimental models of Alzheimers Disease, positively regulates the innate antiviral response during neurotropic virus infection(A25012-38)
Author: Wang Y, Luo W, Wang X, Ma Y, Huang L, Wang Y,, Publication name: , IF: 38
Ang-(1–7)/Mas axis ameliorates bleomycin-induced pulmonary fibrosis in mice via restoration of Nox4-Nrf2 redox homeostasis(A25012-18.20)
Author: Sheng M, Li Q, Huang W, Publication name: European Journal of Pharmacology, IF: 18.20
MTG8 interacts with LHX6 to specify cortical interneuron subtype identity(A25012-17.694)
Author: Asgarian Z, Oliveira MG, Stryjewska A, Publication name: Nature Communications, IF: 17.694
UFMylation maintains tumor suppressor pVHL stability by activating the deubiquitinase BAP1.(A25012-12.500)
Author: Yang, Xiao, et al., Publication name: Science Advances, IF: 12.500
The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis(A25012-11.4)
Author: Yuan, Yueming, et al., Publication name: Redox Biology, IF: 11.4
DIW1 encoding a clade I PP2C phosphatase negatively regulates drought tolerance by dephosphorylating TaSnRK1.1 in wheat(A25012-11.4)
Author: Wang, Jingyi, et al., Publication name: Journal of Integrative Plant Biology, IF: 11.4
DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma(A25012-11.3)
Author: Shan Wei, Jing Xing, Jia Chen, Publication name: Journal of Experimental & Clinical Cancer Research, IF: 11.3
Synthetic dual hormone-responsive promoters enable engineering of plants with broad-spectrum resistance(A25012-10.5)
Author: X Li, G Niu, Y Fan, W Liu, Q Wu, C Yu, J Wang, Publication name: Plant Communications, IF: 10.5
MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway(A25012-9.83)
Author: L An, P Nie, M Chen, Publication name: Journal of Experimental Medicine, IF: 9.83
NTF4 plays a dual role in breast cancer in mammary tumorigenesis and metastatic progression(A25012-9.2)
Author: R Sun, J He, Q Xiang, Y Feng, Y Gong, Publication name: Int J Biol Sci, IF: 9.2
hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility(A25012-8.8)
Author: Wang, **aoli, et al, Publication name: Cell Reports, IF: 8.8
Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression(A25012-7.109)
Author: Zhao B, Ni Y, Zhang H, et al., Publication name: Cell death discovery, IF: 7.109
Caspase-8 drove apoptosis of BMECs to promote neutrophil infiltration and DE205B clearance in meningitis.(A25012-6.900)
Author: Wang, Xuhang, et al., Publication name: Microbiological Research, IF: 6.900
Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1)(A25012-6.7)
Author: Shi, Jiale, et al., Publication name: PLoS Pathogens, IF: 6.7
Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection(A25012-6.50)
Author: S Xue, S Leng, F Zhang, Publication name: Experimental and Therapeutic Medicine, IF: 6.50
PIF/harbinger transposon-derived protein promotes 7SL expression to enhance pathogen resistance.(A25012-6.200)
Author: Geng, Shang, Xing Lv, and Tianjun Xu., Publication name: EMBO reports, IF: 6.200
FTO promotes innate immunity by controlling NOD1 expression via m6A-YTHDF2 manner in teleost(A25012-6.107)
Author: Geng S, Zheng W, Zhao Y, et al., Publication name: Iscience, IF: 6.107
A chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes(A25012-5.9)
Author: Zhu, F., Yin, Z. T., Zhao, Q. S., Sun, Y. X., Jie, Publication name: Communications biology, IF: 5.9
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis(A25012-5.793)
Author: Liu S, Fan M, Xu JX, Yang LJ, Qi CC, Xia QR, Ge JF, Publication name: J Neuroinflammation, IF: 5.793
Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury(A25012-5.75)
Author: Zhe Gong, Jingrui Pan, et al, Publication name: Journal of Neuroinflammation, IF: 5.75
Combination of PARP inhibitor and CDK4/6 inhibitor modulates cGAS/STING‐dependent therapy‐induced senescence and provides “one‐two punch” opportunity(A25012-5.7)
Author: T Wang, W Liu, Q Shen, R Tao, C Li, Q Shen, Publication name: Cancer Science, IF: 5.7
NEK2 induces autophagy‐mediated bortezomib resistance by stabilizing Beclin‐1 in multiple myeloma(A25012-5.64)
Author: J Xia, Y He, B Meng, Publication name: Molecular Oncology, IF: 5.64
AICAR, an AMP-Activated ProteinKinase Activator,Ameliorates Acuteancreatitis-Associated Liver InjuryPartially Through Nrf2-MediatedAntioxidant Effects and Inhibition ofNLRP3 lnflammasome Activation(A25012-5.6)
Author: W Huang, Q Shi, W Liu, Publication name: Frontiers in Pharmacology, IF: 5.6
Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2‐Mediated Degradation of p53(A25012-5.47)
Author: Fujun Jin, Yiliang Wang, et al, Publication name: Stem Cell, IF: 5.47
Angiopoietin-like 4 promotes angiogenesis and neurogenesis in a mouse model of acute ischemic stroke(A25012-5.4)
Author: Z Qiu, J Yang, G Deng, Publication name: Brain Research Bulletin, IF: 5.4
SNX32 is a host restriction factor that degrades African swine fever virus CP204L via the RAB1B-dependent autophagy pathway(A25012-5.4)
Author: Yang, Wenping, et al, Publication name: Journal of Virology, IF: 5.4
Global screening of LUBAC and OTULIN interacting proteins by human proteome microarray(A25012-5.201)
Author: Zhou L, Ge Y, Fu Y, Wu B, Zhang Y, Li L, Cui CP, Wang S, Zhang L, Publication name: Front Cell Dev Biol, IF: 5.201
CTLA-4 Facilitates DNA Damage–Induced Apoptosis by Interacting With PP2A(A25012-5.201)
Author: Yan Q, Zhang B, Ling X, Zhu B, Mei S, Yang H, Zhang D, Huo J, Zhao Z,, Publication name: Front Cell Dev Biol, IF: 5.201
SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction(A25012-5)
Author: Nie, Ying, et al., Publication name: Virus Research, IF: 5
TRIM14 restricts tembusu virus infection through degrading viral NS1 protein and activating type I interferon signaling.(A25012-4.900)
Author: Zhou, Peng, et al., Publication name: PLoS pathogens, IF: 4.900
F0F1 ATP synthase regulates extracellular calcium influx in human neutrophils by interacting with Cav2.3 and modulates neutrophil accumulation in the lipopolysaccharide-challenged lung(A25012-4.83)
Author: B Zhu, Z Feng, Y Guo, Publication name: Cell Communication and Signaling, IF: 4.83
C-Jun/C7ORF41/NF-κB axis mediates hepatic inflammation and lipid accumulation in NAFLD(A25012-4.05)
Author: FJ Yan, X Wang, SE Wang, Publication name: Biochemical Journal, IF: 4.05
The Nucleoprotein and Phosphoprotein of Peste des Petits Ruminants Virus Inhibit Interferons Signaling by Blocking the JAK-STAT Pathway(A25012-4.03)
Author: P Li, Z Zhu, X Zhang, W Dang, L Li, X Du, M Zhang, Publication name: Viruses, IF: 4.03
Peste des petits ruminants virus nucleocapsid protein inhibits interferon-β production by interacting with IRF3 to block its activation(A25012-4.02)
Author: Zixiang Zhu, Pengfei Li, Fan Yang, et al, Publication name: J Virol, IF: 4.02
Disruption of Ssp411 causes impaired sperm head formation and male sterility in mice(A25012-3.99)
Author: Miao Liu, Yanfei Ru, et al, Publication name: Biochimica et Biophysica Acta (BBA) - General Subjects, IF: 3.99
Hepatitis B X-interacting protein promotes the formation of the insulin gene–transcribing protein complex Pdx-1/Neurod1 in animal pancreatic β-cells(A25012-3.92)
Author: Li H, Wang Z, Li Y H, et al, Publication name: JOURNAL OF BIOLOGICAL CHEMISTRY, IF: 3.92
Autographa californica multiple nucleopolyhedrovirus Ac51 interacts with Ac66 and facilitates its nuclear localization to promote the nuclear egress of nucleocapsids.(A25012-3.800)
Author: Qiu, Jianxiang, et al., Publication name: Journal of Virology, IF: 3.800
N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49. 5(A25012-3.7)
Author: C Li, M Wang, A Cheng, Y Wu, B Tian, Publication name: Microbiology Spectrum, IF: 3.7
Transcriptomic analysis reveals potential novel circRNA in goiters progression.(A25012-3.688)
Author: Nie, Guanying, et al., Publication name: Gene, IF: 3.688
Salvia miltiorrhiza Restrains Reactive Oxygen Species-Associated Pulmonary Fibrosis via Targeting Nrf2-Nox4 Redox Balance(A25012-3.51)
Author: LY Peng, L An, NY Sun, Y Ma, XW Zhang, Publication name: The American Journal of Chinese Medicine, IF: 3.51
MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation(A25012-3.5)
Author: Y Hong, M Ye, F Wang, Publication name: Frontiers in Oncology, IF: 3.5
S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma(A25012-3.45)
Author: Yifei Shen, Shujie Zhao, Shenyu Wang, et al, Publication name: EBioMedicine, IF:
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis(A25012-3.171)
Author: Zhou Y, Wen LL, Li YF, Wu KM, Duan RR, Yao YB, Jing LJ, Gong Z, Teng JF, Jia YJ,, Publication name: Neural Regen Res, IF: 3.171
SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia(A25012-3.07)
Author: Q Kong, Y Li, Q Liang, Publication name: Cancer Biology &Therapy, IF: 3.07
MiR-375 impairs the invasive capabilities of hepatoma cells by targeting HIF1α under hypoxia(A25012-2.751)
Author: Chun Wang · Jie Luo · Zhihang Chen, Publication name: Digestive Diseases and Sciences, IF: 2.751
Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection(A25012-2.7)
Author: Xue, Shishan, et al, Publication name: Experimental and Therapeutic Medicine, IF: 2.7
Ginsenoside Rb1 Alleviates Oxidative Low-Density Lipoprotein–Induced Vascular Endothelium Senescence via the SIRT1/Beclin-1/Autophagy Axis(A25012-2.26)
Author: G Shi, D Liu, B Zhou, Publication name: Journal of Cardiovascular Pharmacology, IF: 2.26
A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis(A25012-2.17)
Author: Sun S, Li F, Liu Y, et al, Publication name: Arch Oral Biol, IF: 2.17
Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin‑mediated autophagy(A25012-2.1)
Author: Lin F, Liu Y, Tang L, Xu X, Zhang X, Song Y, Chen B, Ren Y, Yang X,, Publication name: Mol Med Rep, IF: 2.1
7‑Difluoromethyl‑5, 4'‑dimethoxygenistein exerts anti‑angiogenic effects on acute promyelocytic leukemia HL‑60 cells by inhibiting the TLR4/NF‑κB signaling pathway(A25012-1.97)
Author: X Xiang, L Li, P Bo, Publication name: Molecular Medicine Reports, IF: 1.97
DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma(A25012-1.70)
Author: Wei S, **ng J, Chen J, Publication name: Journal of Experimental & Clinical Cancer Research, IF: 1.70
Nuclear localization signal in TRIM22 is essential for inhibition of type 2 porcine reproductive and respiratory syndrome virus replication in MARC-145 cells(A25012-1.51)
Author: H Jing, R Tao, N Dong, S Cao, Y Sun, W Ke, Y Li, Publication name: Virus Genes, October, IF: 1.51
Hsp90 inhibitors directly block HSV-1 DNA replication via inducing degradation of pUL42(A25012-)
Author: S Qin, X Hu, Q Zeng, Z Wang, X Song, Y Wang, Publication name: researchsquare, IF:
Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development(A25012-)
Author: T Yuan, Y Wang, Y Jin, S Xu, H Zhang, Q Chen, N Li, Publication name: biorxiv, IF:
