| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C11H12O3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
iso-Dehydrozingerone is a dehydrozingerone analog that shows moderate in vitro cytotoxic activity against human tumor cells, with IC50 values of 10.0 μg/mL, 8.2 μg/mL and greater than 10 μg/mL against human nasopharyngeal carcinoma cells, multidrug-resistant nasopharyngeal carcinoma cells and human lung cancer cells, respectively. It can be used in studies of nasopharyngeal carcinoma, multidrug-resistant nasopharyngeal carcinoma and lung cancer[1]. It has the molecular formula C11H12O3 and a molecular weight of 192.21 g/mol.
Physical & Chemical Properties
| CAS Number | 22214-39-7 |
|---|---|
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| SMILES | C(=C/C(C)=O)\C1=CC(O)=C(OC)C=C1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
Iso-Dehydrozingerone (2 days) inhibits proliferation of human nasopharyngeal carcinoma KB cells, with an IC50 of 10.0 μg/mL, and of human multidrug-resistant nasopharyngeal carcinoma KB-VCR cells, with an IC50 of 8.2 μg/mL[1].
Cell Cytotoxicity Assay[1]
| Cell Line | Human nasopharyngeal carcinoma KB cells, multidrug-resistant human nasopharyngeal carcinoma KB-VCR cells, human lung carcinoma A549 cells |
|---|---|
| Concentration | Concentrations to determine IC50 values |
| Incubation Time | 2 days |
| Result | Inhibited replication of KB cells with an IC50 of 10.0 μg/mL. Inhibited replication of KB-VCR cells with an IC50 of 8.2 μg/mL. Showed no measurable activity against A549 cells (IC50 >10 μg/mL). |
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).
