| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 5,5,6,6-Tetrachloro-1,1,3,3-tetraethylbenzimidazolylcarbocyanine iodide, , 5,6-dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethylbenzimidazol-3-ium-2-yl)prop-2-enylidene]-1,3-diethylbenzimidazole;iodide, Jc-1; 3520-43-2; JC-1 jodide; JC1 dye; CBIC2(3); 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide |
| Cas No. | |
| Form | Red powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (20 mg/ml) |
| Source | Synthetic |
| Storage |
JC-1 is a cationic dye used to assess mitochondrial membrane potential, a key indicator of mitochondrial health and function. In neuroscience, JC-1 is widely employed to study mitochondrial dysfunction, which is a hallmark of neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS. JC-1 accumulates in mitochondria and exhibits potential-dependent fluorescence shifts, enabling real-time monitoring of mitochondrial depolarization and apoptosis. Its application in neuronal models helps elucidate the role of mitochondrial dynamics in cell survival, oxidative stress, and energy metabolism, contributing to the understanding of neurodegenerative mechanisms.
Details:
This product does not require a Material Safety Data Sheet under the Occupational Safety and Health Administration standard entitled "Hazard Communication" 29 CFR 1910.1200 for the United States.
The product does not meet the criteria of W.H.M.I.S. classification as a controlled product. As a result, a W.H.M.I.S. Material Safety Data Sheet is not required (in Canada) for this product.
JC-1 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-562)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
