| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C8H16N4O7 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Kdo Azide is a click chemistry reagent bearing an azide group and functions as a metabolic labeling reagent[1]. Its azide group allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules bearing DBCO or BCN groups. It is supplied as a white to light yellow solid (C8H16N4O7, MW 280.24) at 99.85% purity.
Physical & Chemical Properties
| CAS Number | 1380099-68-2 |
|---|---|
| Molecular Formula | C8H16N4O7 |
| Molecular Weight | 280.24 g/mol |
| Purity | 99.85% |
| Appearance | Solid |
| Color | White to light yellow |
| SMILES | [N-]=[N+]=NC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CC(C(O)=O)=O.N |
| Signaling Pathway | Antibody-Drug Conjugate/ADC Related |
| Storage | -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
Click chemistry refers to selective, modular, wide-ranging, high-yield chemical reactions that enable rapid synthesis of new compounds by linking heteroatoms (C-X-C). Bertozzi extended click chemistry into a new dimension, bioorthogonal chemistry, which is defined as a rapid and selective reaction that leaves biological processes undisturbed under physiological conditions. Common reaction structures used in click chemistry include Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.
Data provided by the manufacturer.
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