| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | E.coli-derived human KEAP1 recombinant protein (Position: K84-K312) was used as the immunogen for the KEAP1 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
KEAP1 Antibody / Kelch-like ECH-associated protein 1 is an antibody targeting KEAP1. Host: Rabbit. Polyclonal. Format: Lyophilized. Applications: WB, ICC, IF, FACS, ELISA.
Key elements and design rationale
- Target: KEAP1.
- Immunogen: E.coli-derived human KEAP1 recombinant protein (Position: K84-K312) was used as the immunogen for the KEAP1 antibody..
- Species reactivity: Human, Mouse, Rat.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
KEAP1 antibody is designed to target Kelch-like ECH-associated protein 1, a critical regulator of cellular redox balance and stress response. The KEAP1 protein functions as a substrate adaptor protein within a Cullin 3-based E3 ubiquitin ligase complex, where it plays a central role in mediating the ubiquitination and subsequent degradation of nuclear factor erythroid 2-related factor 2 (NFE2L2, also known as NRF2).
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IF/ICC: subcellular localization imaging with proper background controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
