KIR2DS2 Antibody, FITC conjugated

Overview

This polyclonal anti-KIR2DS2 antibody raised in Rabbit, conjugated with FITC. Designed to detect KIR2DS2 in Human for immunology research.

Key elements and design rationale

• Immunogen: Recombinant Human Killer cell immunoglobulin-like receptor 2DS2 protein (104-241AA) — determines epitope; confirm sample prep compatibility.
• Host (Rabbit): Requires anti-rabbit-IgG secondary matching isotype IgG.
• Polyclonal: Multiple epitopes = robust signal; lot-to-lot variability — include controls.
• Isotype (IgG): Match secondary, Protein A/G, and isotype controls to IgG.
• Purification (Protein G purification): Enriches Ig classes; reduces non-specific background.
• FITC: Direct fluorescence (Ex490/Em525); protect from light; use antifade.

Biological background

KIR2DS2 (also: 183ActI, CD158 antigen like family member J, CD158b, CD158J, CD158j antigen, cl 49, KI2S2_HUMAN, killer cell Ig like receptor, Killer cell immunoglobulin-like receptor 2DS2, Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1, KIR2DS2, MHC class I NK cell receptor, Natural killer associated transcript 5, natural killer cell inhibitory receptor, NK receptor 183 Actl, NKAT 5, NKAT5, p58 killer cell inhibitory receptor KIR K7a, p58 KIR, p58 natural killer cell receptor clone CL 49, p58 NK receptor CL 49) — studied in Human systems. Expression, localization, and PTMs vary across cell types and disease states. Consult UniProt, NCBI Gene, and primary literature for current KIR2DS2 annotation relevant to immunology.

Common research applications

• Refer to product documentation for confirmed application data.

Notes for experimental interpretation

• Isotype controls: IgG from Rabbit at equivalent concentration.
• Cross-reactivity: Polyclonal: validate with KO/KD controls.
• Matrix effects: Verify dilution linearity in your sample matrix.
• Reactivity: Confirmed for Human; extrapolation requires validation.

This product is a polyclonal antibody purified from rabbit antiserum.

• Datasheet (12555068)

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.