| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C30H36FN5O4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
KRAS G12D modulator-1 is described as a potent modulator of KRAS G12D, with IC50 values ranging from 1 to 10 μM for NEA-G12D, PPI-G12D, and p ERK-AGS, respectively. It can be used in cancer research[1]. The compound has the molecular formula C30H36FN5O4 and a molecular weight of 549.64 g/mol.
Physical & Chemical Properties
| CAS Number | 2883034-05-5 |
|---|---|
| Molecular Formula | C30H36FN5O4 |
| Molecular Weight | 549.64 g/mol |
| SMILES | OC1=CC(C=CC=C2)=C2C(N3CC4=NC(OC[C@@]56N(CCC6)C[C@@H](C5)F)=NC(N7C[C@@H](C[C@H](C7)O)O)=C4CC3)=C1 |
| Signaling Pathway | GPCR/G Protein; MAPK/ERK Pathway |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Hong L, et al. Kras modulators and uses thereof. WO2022261210.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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