| Field | Specification |
|---|---|
| Alternative names | (3R,4S)-3,4-Dihydroxyoxolan-2-one |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C4H6O4 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
L-Threonolactone, also known as (3R,4S)-3,4-Dihydroxyoxolan-2-one, is classified by the manufacturer as a purine nucleoside analog. Analogs of this class show broad antitumor activity against indolent lymphoid malignancies, acting through inhibition of DNA synthesis and induction of apoptosis, among other mechanisms[1]. It is supplied as a white to off-white solid (C4H6O4, MW 118.09) at 98.0% purity.
Physical & Chemical Properties
| CAS Number | 21730-93-8 |
|---|---|
| Molecular Formula | C4H6O4 |
| Molecular Weight | 118.09 g/mol |
| Purity | 98.0% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O[C@@H](CO1)[C@@H](O)C1=O |
| Signaling Pathway | Cell Cycle/DNA Damage |
| Solubility | In Vitro: DMSO: 83.33 mg/mL (705.65 mM; Requires sonication; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 83.33 mg/mL (705.65 mM) | requires sonication; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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