| Field | Specification |
|---|---|
| Alternative names | VNRX-5236 |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C12H14BNO5 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Ledaborbactam, also known as VNRX-5236, is a β-lactamase inhibitor (WO2015191907, Example 62) that can be used in research on bacterial infections[1]. It is supplied as a white to off-white solid (C12H14BNO5, MW 263.05) at 99.12% purity.
Physical & Chemical Properties
| CAS Number | 1842397-36-7 |
|---|---|
| Molecular Formula | C12H14BNO5 |
| Molecular Weight | 263.05 g/mol |
| Purity | 99.12% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | OC(C1=C2C(C[C@@H](B(O2)O)NC(CC)=O)=CC=C1)=O |
| Signaling Pathway | Anti-infection |
| Solubility | In Vitro: DMSO: ≥ 100 mg/mL (380.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) * "≥" means soluble, but saturation unknown. |
| Storage | -20°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. WO2015191907
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | ≥ 100 mg/mL (380.16 mM) | use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); protect from light; avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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