| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C27H30N2O7S2 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Lissamine rhodamine B is a red-fluorescent dye and a derivative of rhodamine. It can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays[1][2]. It is supplied as a brown to black solid (C27H30N2O7S2, MW 558.67) at 96.67% purity.
Physical & Chemical Properties
| CAS Number | 2609-88-3 |
|---|---|
| Molecular Formula | C27H30N2O7S2 |
| Molecular Weight | 558.67 g/mol |
| Purity | 96.67% |
| Appearance | Solid |
| Color | Brown to black |
| SMILES | O=S(C1=CC=C(C2=C3C=CC(N(CC)CC)=CC3=[O+]C4=C2C=CC(N(CC)CC)=C4)C(S(=O)([O-])=O)=C1)(O)=O |
| Solubility | In Vitro: H2O: 5 mg/mL (8.95 mM; Requires sonication and warming and heat to 60°C) |
| Storage | Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| H2O | 5 mg/mL (8.95 mM) | requires sonication and warming and heat to 60°C |
Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); avoid repeated freeze-thaw cycles.
If water is used as the stock solvent, dilute to the working solution and sterilize it through a 0.22 μm filter before use.
Data provided by the manufacturer.
In Vitro
Lissamine rhodamine B (1 mg; 1 h; room temperature; dark) can serve to detect ochratoxin A (OTA), a common mycotoxin[1]. Lissamine rhodamine B has fluorescence properties; the detection conditions are excitation at 555 nm and fluorescence emission spectrum detection at 580 nm[1].
In Vivo
Lissamine rhodamine B can serve as a radiotracer for imaging tumor mice by positron emission tomography (PET)[2].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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Crosstalk-Free, High-Resolution Pressure Sensor Arrays Enabled by High-Throughput Laser Manufacturing. Adv Mater 2022 May;34(21):e2200517. PMID: 35332964
Exogenous Phytohormone Activators Enhance Rice Resistance to Brown Planthoppers by Boosting the Phenylpropanoid Pathway under Elevated CO2. J Agric Food Chem 2026 Mar 18;74(10):8368-8379. PMID: 41781190
Selective anti-cancer effects of cannabidiol and Δ9-tetrahydrocannabinol via PI3K/AKT/mTOR inhibition and PTEN restoration in ovarian cancer cells. Front Pharmacol 2025 Dec 15:16:1693129. PMID: 41472794
Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response against Mycobacteria. Mol Pharm 2024 May 6;21(5):2238-2249. PMID: 38622497
University of Ottawa. 2025.
bioRxiv. 2024 Apr 17.
