| Field | Specification |
|---|---|
| Alternative names | Litarex |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C6H5Li3O7 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Lithium citrate, also known as Litarex, is a lithium supplement that reduces excess brain N-acetylaspartate (NAA) in Canavan disease, an autosomal recessive leukodystrophy caused by mutations in the aspartate acylase (ASPA) gene, the enzyme that catalyzes hydrolysis of NAA to acetate and aspartate[1]. It is supplied as an off-white to light yellow solid (C6H5Li3O7, MW 209.92) at 98.0% purity.
Physical & Chemical Properties
| CAS Number | 919-16-4 |
|---|---|
| Molecular Formula | C6H5Li3O7 |
| Molecular Weight | 209.92 g/mol |
| Purity | 98.0% |
| Appearance | Solid |
| Color | Off-white to light yellow |
| SMILES | O=C(CC(C(O[Li])=O)(CC(O[Li])=O)O)O[Li] |
| Storage | 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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Lithocholic acid phenocopies anti-ageing effects of calorie restriction. Nature 2025 Jul;643(8070):192-200. PMID: 39695227
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Bacterial vesicles from intratumoral L. salivarius enhance PD-1 blockade via FPR1-mediated macrophage polarization in gastric cancer. Cell Rep Med 2026 Feb 17;7(2):102621. PMID: 41707647
Flavonoid-mediated metabolic underpinning quality variation in red bud-sport pear mutants. Food Chem 2025 Oct 15:489:144992. PMID: 40466530
Discovery of novel ascorbic acid derivatives and other metabolites in fruit of Rosa roxburghii Tratt through untargeted metabolomics and feature-based molecular networking. Food Chem 2023 Mar 30;405(Pt A):134807. PMID: 36370576
Food Res Int. 2026 Feb 6.
Homogentisic acid metabolism inhibits papillary thyroid carcinoma proliferation through ROS and p21-induced cell cycle arrest. Life Sci 2024 Jun 15:347:122682. PMID: 38702025
Hepatotoxicity prediction for traditional Chinese medicine: a two-step in silico framework integrating network and machine learning approaches. BMC Complement Med Ther 2026 Apr 2;26(1):177. PMID: 41923057
Cell Metabolomics Reveals the Hepatotoxic Mechanism of Copper in Normal Rat Liver Cells Using Reversed-Phase and Hydrophilic Interaction Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry. J Sep Sci 2025 Nov;48(11):e70312. PMID: 41172059
New J Chem. 03 Aug 2022.
