| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | LY-2523355 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Litronesib (CAS 910634-41-2) is a research-grade small molecule supplied by TargetMol.
Alternative names: LY-2523355
Physical Properties
| CAS Number | 910634-41-2 |
|---|---|
| Molecular Formula | C23H37N5O4S2 |
| Molecular Weight | 511.70 g/mol |
| SMILES | C(NS(CCNCC)(=O)=O)(C)1(N(C(C(C)(C)C)=O)N=C(NC(C(C)(C)C)=O)S1)C2=CC=CC=… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
Target(s): Kinesin
Signaling pathway(s): Cytoskeletal Signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Stock concentration (mM) = [mass (mg) × 1000] / [MW (g/mol) × volume (mL)]. Example: to prepare 10 mM stock from 5 mg of a 500 g/mol compound: volume = (5 × 1000) / (500 × 10) = 1 mL DMSO. For working solutions, dilute the DMSO stock into assay buffer: C₁V₁ = C₂V₂. For a 1 µM working solution from a 10 mM stock in a 1 mL assay volume, add 0.1 µL of stock (or pre-dilute to an intermediate concentration first).
The concentration of stock solution should be lower than the solubility provided on the official website. Within this range, the concentration of stock solution should be set based on that of working solution. For cell experiments, it is recommended to set the stock solution concentration at least 1000 times higher than that of working solution.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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