| Field | Specification |
|---|---|
| Activity | |
| Alternative Names | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl (2S)-2-methylbutanoate, Mevinolin |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 50 mM in ethanol and 100 mM in DMSO |
| Source | Synthetic |
| Storage |
Lovastatin is a member of the statin class of drugs that inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis. Beyond its cardiovascular benefits, lovastatin has been investigated for its neuroprotective effects, including anti-inflammatory and antioxidant properties. In neuroscience, it is studied for its potential to modulate amyloid precursor protein processing, reduce neuroinflammation, and improve cognitive function in models of Alzheimer's disease. Its pleiotropic effects make it a candidate for repurposing in neurodegenerative disease research.
Classification: Harmful. May be harmful if inhaled, swallowed, or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R62- Possible risk of impaired fertility
Lovastatin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-256)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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