| Field | Specification |
|---|---|
| Target | |
| Alternative names | E3 ubiquitin-protein ligase LRSAM1|Leucine-rich repeat and sterile alpha motif-containing protein 1|RING-type E3 ubiquitin transferase LRSAM1|Tsg101-associated ligase (hTAL)|LRSAM1|TAL |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | leucine rich repeat and sterile alpha motif containing 1 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic(EGF receptors) and exocytic(HIV-1 viral proteins) cargos(PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens(PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation(xenophagy)(PubMed:23245322, PubMed:25484098).
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes LRSAM1. It is validated for ELISA, Western Blot, Immunohistochemistry, Immunofluorescence.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry, Immunofluorescence |
|---|---|
| WB | 1:500-1:2000 |
| IHC | 1:20-1:200 |
| IF | 1:20-1:200 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
leucine rich repeat and sterile alpha motif containing 1
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Immunogen | leucine rich repeat and sterile alpha motif containing 1 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 84 kDa |
| UniProt # | Q6UWE0 |
| Gene ID | 90678 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | E3 ubiquitin-protein ligase LRSAM1|Leucine-rich repeat and sterile alpha motif-containing protein 1|RING-type E3 ubiquitin transferase LRSAM1|Tsg101-associated ligase (hTAL)|LRSAM1|TAL |
Reactivity Notes
Validated reactivity: Human, Mouse. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
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Explore related antibodies and reagents for LRSAM1 research from Fine Test, or contact us for alternative formats.
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