| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-one |
| Cas No. | |
| Form | White Crystalline Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 5 mM in ethanol and to 25 mM in DMSO |
| Source | Synthetic |
| Storage |
LY 294002 is a synthetic small molecule that functions as a potent inhibitor of phosphoinositide 3-kinases (PI3Ks). By blocking PI3K activity, it disrupts the PI3K/Akt signaling pathway, which is critical for cell survival, proliferation, and metabolism. In neuroscience, LY 294002 is widely used to study mechanisms of neuronal apoptosis, synaptic plasticity, and neuroinflammation. Its ability to modulate neurotrophic signaling makes it a valuable tool for investigating neurodegenerative diseases such as Alzheimer's and Parkinson's.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
LY 294002 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-252)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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