| Field | Specification |
|---|---|
| Alternative names | NCC1048 free base |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C21H25F2NO |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
LY393615 free base, also known as NCC1048 free base, is a novel neuronal Ca2+ (calcium channel) and Na+ (sodium channel) blocker, with IC50s of 1.9 μM and 5.2 μM for the α1A and α1B calcium channel subunits. It has good brain penetration and neuroprotective effects in models of cerebral ischemia, and it can be used for neurological disease research[1]. It has the molecular formula C21H25F2NO and a molecular weight of 345.43 g/mol.
Physical & Chemical Properties
| CAS Number | 774528-12-0 |
|---|---|
| Molecular Formula | C21H25F2NO |
| Molecular Weight | 345.43 g/mol |
| SMILES | FC1=CC=C(C2(C3=CC=C(C=C3)F)OC(CC2)CNCCCC)C=C1 |
| Signaling Pathway | Membrane Transporter/Ion Channel; Neuronal Signaling |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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