Mal-PEG3-C1-NHS ester

SKU:BHB21900880
Overview
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Mal-PEG3-C1-NHS ester (CAS 2230016-26-7) is an ADC linker supplied as a liquid. Relevant to Antibody-Drug Conjugate/ADC Related research. Molecular formula C16H20N2O9, molecular weight 384.34 g/mol.
Purity 95.0%
CAS Number 2230016-26-7
Molecular Weight 384.34 g/mol
Form Liquid
Storage -20°C as supplied
Options selector
Catalog no. Size
HY-133581-5MG 5 mg (50 μL x 260.19 mM in DMSO)
HY-133581-10MG 10 mg (100 μL x 260.19 mM in DMSO)
HY-133581-25MG 25 mg (250 μL x 260.19 mM in DMSO)
HY-133581-50MG 50 mg (500 μL x 260.19 mM in DMSO)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg (50 μL x 260.19 mM in DMSO), 10 mg (100 μL x 260.19 mM in DMSO), 25 mg (250 μL x 260.19 mM in DMSO), 50 mg (500 μL x 260.19 mM in DMSO)
  • Lead time: shown per option in the variant selector.
  • Storage: Solution, -20°C, 2 years.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: transfer to -20°C as soon as possible.
Field Specification
CAS no. 2230016-26-7
Applications
  • Functional Assay (In Vitro)
Molecular weight 384.34
Molecular formula C16H20N2O9
Purity 95.0%
SMILES O=C(ON1C(CCC1=O)=O)COCCOCCOCCN2C(C=CC2=O)=O
Form Liquid
Storage Solution, -20°C, 2 years.
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-133581
Main SKU BHB21900880
ADC Linkers & Payloads

Compound Overview

Mal-PEG3-C1-NHS ester functions as a non-cleavable, 3-unit PEG linker in the synthesis of antibody-drug conjugates (ADCs)[1]. It is supplied as a colorless to light yellow liquid (C16H20N2O9, MW 384.34) at 95.0% purity.

Physical & Chemical Properties

CAS Number 2230016-26-7
Molecular Formula C16H20N2O9
Molecular Weight 384.34 g/mol
Purity 95.0%
Appearance Liquid
Color Colorless to light yellow
SMILES O=C(ON1C(CCC1=O)=O)COCCOCCOCCN2C(C=CC2=O)=O
Signaling Pathway Antibody-Drug Conjugate/ADC Related
Storage Solution, -20°C, 2 years.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
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  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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