| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | MB07729 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
MB-07729 (CAS 882755-95-5) is a research-grade small molecule supplied by TargetMol.
Alternative names: MB07729
Physical Properties
| CAS Number | 882755-95-5 |
|---|---|
| Molecular Formula | C12H15N2O5PS |
| Molecular Weight | 330.30 g/mol |
| SMILES | C(C(C)(C)C)(=O)C1=C(N=C(N)S1)C=2OC(P(=O)(O)O)=CC2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
MB-07729 is a potent non-competitive inhibitor of fructose-1,6-bisphosphate with IC50 values of 189, 121 and 31 nM in rat, monkey and human, respectively, for the study of diabetes.
Target(s): Phosphatase
Signaling pathway(s): Metabolism
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.
Use a bath-type ultrasonic cleaner rather than a high-intensity ultrasonic disruptor. Bath sonicators provide gentle, uniform agitation appropriate for dissolving solid compounds without generating cavitation damage or excessive heat. Ensure the solvent tube is fully submerged and use short sonication pulses of 5–10 seconds.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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