| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C25H29Cl2N3Pt |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Mcl-1 inhibitor 16 is a mitochondrial-targeting, platinum-based inhibitor of Mcl-1. It induces Bax/Bak-dependent apoptosis in cancer cells and can be used alone or in combination with ABT-199, showing anti-tumor activity[1]. It has a molecular formula of C25H29Cl2N3Pt and a molecular weight of 637.51 g/mol.
Physical & Chemical Properties
| CAS Number | 3036411-36-3 |
|---|---|
| Molecular Formula | C25H29Cl2N3Pt |
| Molecular Weight | 637.51 g/mol |
| SMILES | Cl[Pt]1([N](C=CC2=C3N(CCCCCCCCC)C4=CC=CC=C24)=C3C5=CC=CC=[N]51)Cl |
| Signaling Pathway | Apoptosis |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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Schisandra chinensis (Turcz.) Baill neutral polysaccharides alleviate Parkinson's disease via effectively activating MCL-1 expression regulation of autophagy signaling. Int J Biol Macromol 2024 Aug 26;279(Pt 1):134952. PMID: 39197630
