| Field | Specification |
|---|---|
| Alternative names | [(1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, Ametycine |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C15H18N4O5 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | May be dissolved in DMSO (15mg/mL); or water (1mg/mL, warm) |
| SMILES | |
| InChIKey | |
| Form | Dark Purple Crystalline Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Mitomycin C is a DNA crosslinking agent that undergoes reductive activation followed by sequence-specific alkylation. It is used in neuroscience to induce DNA damage and study cellular responses such as apoptosis and repair mechanisms. Its potent genotoxic effects make it a valuable compound for modeling neurodegenerative processes involving DNA integrity.
Classification: Very toxic. May be fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
- R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed
- R46 - May cause heritable genetic damage
- R61 - May cause harm to the unborn child
- R62 - Possible risk of impaired fertility
Hazard Phrases:
H302-H351
Precautionary Phrases:
P281
Mitomycin C (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-246)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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